Bicarbonate

Bicarbonate

SCHEMBL4349495

N.N.O.O.O=C(O)O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9151983 1.00 CA1 (0.71)
Bicarbonate SCHEMBL4349491 1.00
Bicarbonate SCHEMBL867107 1.00
Bicarbonate SCHEMBL11786088 1.00
Bicarbonate SCHEMBL9151976 1.00
Bicarbonate SCHEMBL867106 1.00
Bicarbonate SCHEMBL10680457 1.00 CA1 (0.71)
Bicarbonate SCHEMBL3344078 1.00
Bicarbonate SCHEMBL10581921 0.94 CA1 (0.62)
Bicarbonate SCHEMBL2359529 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544496-B2 Process for making organic/inorganic composites UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-06-09 US claimed
US-7455854-B2 Fluid swellable fibrous matrix containing minerals; artificial bone UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-11-25 US claimed
EP-1793839-A2 FIBROUS MINERALS, METHODS FOR THEIR PRODUCTION USING A SOLUTION-PRECURSOR-SOLID MECHANISM, AND METHODS OF USE UNIVERSITY OF FLORIDA (US) 2007-06-13 EP claimed
EP-1744793-A2 BIOMIMETIC ORGANIC/INORGANIC COMPOSITES, PROCESSES FOR THEIR PRODUCTION, AND METHODS OF USE University of Florida (US) 2007-01-24 EP claimed
US-20060204580-A1 Biomimetic organic/inorganic composites, processes for their production, and methods of use NATIONAL SCIENCE FOUNDATION 2006-09-14 US claimed
WO-2005117918-A2 FIBROUS MINERALS, METHODS FOR THEIR PRODUCTION USING A SOLUTION-PRECURSOR-SOLID MECHANISM, AND METHODS OF USE UNIVERSITY OF FLORIDA (US) 2005-12-15 WO claimed
WO-2005081699-A2 BIOMIMETIC ORGANIC/INORGANIC COMPOSITES, PROCESSES FOR THEIR PRODUCTION, AND METHODS OF USE UNIVERSITY OF FLORIDA (US) 2005-09-09 WO claimed
US-20050152990-A1 Fibrous minerals, methods for their production using a solution-precursor-solid mechanism, and methods of use FLORIDA, UNIVERSITY OF 2005-07-14 US claimed
US-20040131562-A1 Biomimetic organic/inorganic composites, processes for their production, and methods of use UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2004-07-08 US claimed
US-7455854-B2 Fluid swellable fibrous matrix containing minerals; artificial bone UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-11-25 US disclosed
EP-1793839-A2 FIBROUS MINERALS, METHODS FOR THEIR PRODUCTION USING A SOLUTION-PRECURSOR-SOLID MECHANISM, AND METHODS OF USE UNIVERSITY OF FLORIDA (US) 2007-06-13 EP disclosed
WO-2005117918-A2 FIBROUS MINERALS, METHODS FOR THEIR PRODUCTION USING A SOLUTION-PRECURSOR-SOLID MECHANISM, AND METHODS OF USE UNIVERSITY OF FLORIDA (US) 2005-12-15 WO disclosed
US-20050152990-A1 Fibrous minerals, methods for their production using a solution-precursor-solid mechanism, and methods of use FLORIDA, UNIVERSITY OF 2005-07-14 US disclosed