SCHEMBL4349953

SCHEMBL4349953

CCCCCCCC[SiH](C)O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
DNM1 Q05193 5/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29023772 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10605585 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10607059 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL16867583 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10619658 1.00
SCHEMBL2918465 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10603691 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10607107 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL10605603 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1
SCHEMBL8592683 1.00 TSHR (0.47) TSHRTHRBALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113529417-B Water-based organic silicon permeable anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2023-06-30 CN claimed
CN-113529417-A Water-based organic silicon permeation type anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2021-10-22 CN claimed
WO-2024017471-A1 DEFOAMING COMPOSITIONS FOR DETERGENTS WACKER CHEMIE AG (DE) 2024-01-25 WO disclosed
CN-113529417-B Water-based organic silicon permeable anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2023-06-30 CN disclosed
CN-110267730-B Modified siloxane composite membrane for heavy hydrocarbon recovery 沙特阿拉伯石油公司 2022-02-01 CN disclosed
CN-113529417-A Water-based organic silicon permeation type anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2021-10-22 CN disclosed
US-10253168-B2 Additive composition for amine hardeners, use of said additive composition, and amine hardener composition containing said additive composition HILTI AKTIENGESELLSCHAFT (LI) 2019-04-09 US disclosed
US-20160075861-A1 Additive Composition for Amine Hardeners, Use of Said Additive Composition, and Amine Hardener Composition Containing Said Additive Composition HILTI AKTIENGESELLSCHAFT (LI) 2016-03-17 US disclosed
US-9000092-B2 Rubber composition comprising a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-04-07 US disclosed
US-7566750-B2 Defoamer compositions WACKER CHEMIE AG (DE) 2009-07-28 US disclosed
US-20060160908-A1 Defoamer compositions WACKER CHEMIE AG (DE) 2006-07-20 US disclosed
EP-0329279-B1 Silicone release compositions MINNESOTA MINING & MFG (US) 1993-10-20 EP disclosed
EP-0329279-A2 Silicone release compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-23 EP disclosed
US-4822687-A EPOXYPOLYSILOXANE COMPOSITE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-18 US disclosed
US-4371600-A Release overcoat for photoresponsive device XEROX CORPORATION (US) 1983-02-01 US disclosed
US-4275133-A Electrophotographic imaging processes utilizing adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1981-06-23 US disclosed
US-4181772-A Adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1980-01-01 US disclosed