Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430268 | 1.00 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL4350687 | 1.00 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL4214405 | 0.90 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL4214402 | 0.90 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1838608 | 0.85 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL1951359 | 0.84 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3404974 | 0.82 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL2819381 | 0.82 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14388369 | 0.82 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL1712573 | 0.80 | KCNH2 (0.46) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041145-A1 | AZATRICYCLIC COMPOUNDS AND THEIR USE | Glaxo Group Limited (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003690-A1 | AZATRICYCLIC COMPOUNDS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2008-01-10 | — | — | WO | disclosed |