SCHEMBL43509

SCHEMBL43509

Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 1.00
TSHR P16473 7/20 0.54
GAA P10253 4/20 0.54
POLB P06746 2/20 0.54
KDM4E B2RXH2 2/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 8/20 0.52
MAPK1 P28482 1/20 0.52
CDC25B P30305 1/20 0.47
CASP6 P55212 1/20 0.47
RCE1 Q9Y256 1/20 0.47
ALOX15 P16050 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ESR2 Q92731 1/20 0.43
THRB P10828 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30097830 1.00 CYP3A4 (1.00) CYP3A4TSHRGAAPOLBKDM4E
Ammonia Solution, Strong SCHEMBL9140534 0.98 CYP3A4 (0.95) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL8765734 0.98 CYP3A4 (0.95) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL11058899 0.93 CYP3A4 (0.87) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL11482589 0.91 CYP3A4 (0.83) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL5271470 0.91 CYP3A4 (0.83) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL10714891 0.91 CYP3A4 (0.83) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL6351215 0.89 CYP3A4 (0.80) CYP3A4TSHRGAAPOLBKDM4E
SCHEMBL11229105 0.88 CYP3A4 (0.77) CYP3A4TSHRGAAPOLBKDM4E
Benzidine SCHEMBL10749789 0.88 CYP3A4 (0.77) CYP3A4TSHRGAAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12142 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4098400-B1 POLISHING PAD AND METHOD FOR PREPARING A SEMICONDUCTOR DEVICE USING THE SAME ENPULSE CO LTD (KR) 2026-04-22 EP claimed
EP-4724510-A1 USE OF POLYURETHANE ELASTOMERS BASED ON OR USE OF KIT-OF-PARTS COMPRISING MDI-POLYADIPATE PREPOLYMERS AND POLYAMINE CHAIN-EXTENDERS IN PULP AND PAPER APPLICATIONS, PREFERABLY IN THE MANUFACTURE OF DIE CUTTING PADS, ANVIL COVERS, ROLLERS AND ZERO CRUSH WHEELS Covestro Deutschland AG (DE) 2026-04-15 EP claimed
US-20260091462-A1 PAD FOR CHEMICAL MECHANICAL POLISHING DUPONT ELECTRONIC MAT HOLDING INC (US) 2026-04-02 US claimed
US-12570029-B2 Method for manufacturing polishing pad window, and polishing pad window manufactured thereby KPX Chemical Co., Ltd (KR) 2026-03-10 US claimed
CN-121574341-A Thermoplastic polyurethane elastomer, polyurethane foam material, preparation method and application thereof 万华化学集团股份有限公司 2026-02-27 CN claimed
EP-4700054-A1 THERMALLY DEBONDABLE ONE-COMPONENT POLYUREA ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2026-02-25 EP claimed
US-12544025-B2 Determining a biological tissue structural marker for diagnosis of a disease Arion Diagnostics, Inc. (US) 2026-02-10 US claimed
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4676995-A1 CURABLE MASS, METHOD FOR JOINING, CASTING AND COATING SUBSTRATES AND USE OF THE MASS DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) 2026-01-14 EP claimed
US-12515295-B2 Polishing pad and method for preparing a semiconductor device using the same ENPULSE CO., LTD. (KR) 2026-01-06 US claimed
US-4054545-A Process for the preparation of flexible polyurethane foams RHONE-POULENC INDUSTRIES (FR) 1977-10-18 US claimed
US-4039719-A POLYURETHANE ELASTOMER PPG INDUSTRIES, INC. (US) 1977-08-02 US claimed
US-4036906-A NONHYDROLYZING THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-07-19 US claimed
US-4024088-A LECITHIN UNION CARBIDE CORPORATION (US) 1977-05-17 US claimed
US-4009228-A TACKIFIERS FOR RUBBERS AND THERMOPLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-02-22 US claimed
US-3980606-A Polyurethane elastomers having prolonged flex life and tires made therefrom THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-09-14 US claimed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US claimed
US-3959191-A Novel hydrophobic polyurethane foams W. R. GRACE & CO. (US) 1976-05-25 US claimed
US-3939106-A Energy absorbing polyurethane-polyurea cellular elastomers UNION CARBIDE CORPORATION (US) 1976-02-17 US claimed
US-3937474-A Golf club with polyurethane insert ACUSHNET COMPANY (US) 1976-02-10 US claimed