Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981363 | 0.79 | ACE (0.43) | NR1H4SMN1; SMN2SRD5A2KMT2AMEN1 | |
| SCHEMBL1981859 | 0.79 | ACE (0.43) | NR1H4SMN1; SMN2SRD5A2KMT2AMEN1 | |
| SCHEMBL1981863 | 0.79 | ACE (0.43) | NR1H4SMN1; SMN2SRD5A2KMT2AMEN1 | |
| SCHEMBL16695297 | 0.71 | NOTUM (0.74) | NOTUM | |
| SCHEMBL19904634 | 0.71 | NOTUM (0.74) | NOTUM | |
| SCHEMBL3156003 | 0.70 | CA12 (0.60) | KMT2AALOX15MAPT | |
| SCHEMBL985184 | 0.70 | NOTUM (0.60) | KMT2AMEN1ALDH1A1HTTHPGD | |
| SCHEMBL17322964 | 0.69 | ACACB (0.48) | NR1H4SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL12125914 | 0.68 | NOTUM (0.44) | ALDH1A1HTTHPGDNOTUMNPC1 | |
| SCHEMBL4777114 | 0.68 | ACACB (0.44) | NR1H4SMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096907-A1 | AZIRIDINE SYNTHESIS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2009-08-06 | — | — | WO | disclosed |