SCHEMBL4351206

SCHEMBL4351206

CCOC(=O)OC[C@H]1O[C@@H](Oc2ccccc2Cc2ccc(CC)cc2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 19/20 0.84
▸ SLC5A1 P13866 12/20 0.84
▸ TYMP P19971 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4351209 1.00 SLC5A2 (0.84) SLC5A2SLC5A1TYMP
SCHEMBL4359344 0.94 SLC5A2 (0.84) SLC5A2SLC5A1TYMP
SCHEMBL4359343 0.94 SLC5A2 (0.84) SLC5A2SLC5A1TYMP
SCHEMBL4006195 0.92 SLC5A2 (0.81) SLC5A2SLC5A1
SCHEMBL4006197 0.92 SLC5A2 (0.81) SLC5A2SLC5A1
SCHEMBL5343994 0.92 SLC5A2 (0.75) SLC5A2SLC5A1TYMP
SCHEMBL4367084 0.92 SLC5A2 (0.75) SLC5A2SLC5A1TYMP
Sergliflozin Etabonate SCHEMBL23731198 0.91 SLC5A2 (1.00) SLC5A2SLC5A1
Sergliflozin Etabonate SCHEMBL18058588 0.91 SLC5A2 (1.00) SLC5A2SLC5A1
Sergliflozin Etabonate SCHEMBL621808 0.91 SLC5A2 (1.00) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1782828-B1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT KISSEI PHARMACEUTICAL (JP) 2016-06-29 — — EP disclosed
US-8951976-B2 Progression inhibitor for disease attributed to abnormal accumulation of liver fat KISSEI PHARMACEUTICAL CO., LTD. (JP) 2015-02-10 — — US disclosed
US-20090286751-A1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT KISSEI PHARMACEUTICAL CO., LTD. (JP) 2009-11-19 — — US disclosed
US-20080045466-A1 Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-02-21 — — US disclosed
EP-1782828-A1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT Kissei Pharmaceutical Co., Ltd. (JP) 2007-05-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045466-A1 Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat SLC10A1, SLC2A2, SLC2A1 SLC5A2 10/4885SLC5A1 12/4885TYMP 3589/4885
US-20090286751-A1 PROGRESSION INHIBITOR FOR DISEASE ATTRIBUTED TO ABNORMAL ACCUMULATION OF LIVER FAT FABP1, SLC2A1, SLC10A1 SLC5A2 11/4885SLC5A1 15/4885TYMP 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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