Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 3/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903716 | 1.00 | HRH3 (0.45) | HRH3HRH4ADH1AADH1CABCB11 | |
| SCHEMBL20839242 | 1.00 | HRH3 (0.45) | HRH3HRH4ADH1AADH1CABCB11 | |
| SCHEMBL20055097 | 0.95 | — | — | |
| SCHEMBL1847965 | 0.86 | — | — | |
| SCHEMBL3186493 | 0.80 | HRH3 (0.42) | HRH3HRH4ADH1AADH1CABCB11 | |
| Hydrochloric Acid SCHEMBL27567168 | 0.78 | HRH4 (0.41) | HRH3HRH4ADH1AADH1CABCB11 | |
| Hydrochloric Acid SCHEMBL6897821 | 0.78 | HRH4 (0.41) | HRH3HRH4ADH1AADH1CABCB11 | |
| SCHEMBL7691331 | 0.78 | HRH3 (0.48) | HRH3HRH4ADH1AADH1CABCB11 | |
| SCHEMBL24951938 | 0.77 | HRH4 (0.39) | HRH3HRH4ADH1AADH1CABCB11 | |
| SCHEMBL7857024 | 0.77 | PIK3CD (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |