Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 12/20 | 0.55 |
| ▸ | HCN1 | O60741 | 11/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706796 | 0.91 | HCN4 (0.56) | HCN4HCN1ALDH1A1TSHRTP53 | |
| SCHEMBL13706765 | 0.91 | HCN4 (0.60) | HCN4HCN1P2RX7ALDH1A1TSHR | |
| SCHEMBL13706860 | 0.91 | HCN4 (0.55) | HCN4HCN1P2RX7MC4RALDH1A1 | |
| SCHEMBL13706772 | 0.90 | HCN4 (0.54) | HCN4HCN1P2RX7ALDH1A1TSHR | |
| SCHEMBL4358152 | 0.89 | HCN4 (0.55) | HCN4HCN1P2RX7MC4RSLC6A9 | |
| SCHEMBL13706783 | 0.88 | HCN4 (0.51) | HCN4HCN1P2RX7MC4RALDH1A1 | |
| SCHEMBL13706785 | 0.87 | HCN4 (0.51) | HCN4HCN1P2RX7MC4RALDH1A1 | |
| SCHEMBL13706867 | 0.85 | HCN4 (0.49) | HCN4HCN1P2RX7MC4RALDH1A1 | |
| SCHEMBL13706754 | 0.84 | HCN4 (0.43) | HCN4HCN1P2RX7ALDH1A1TSHR | |
| SCHEMBL13706954 | 0.84 | HCN4 (0.43) | HCN4HCN1P2RX7ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |