SCHEMBL4352376

SCHEMBL4352376

O=P(O)(O)OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
KDM4E B2RXH2 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GAA P10253 1/20 0.38
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28529946 0.94 KDM4E (0.59) TSHRKDM4ETDP1GAA
SCHEMBL19412160 0.85 KDM4E (0.47) TSHRKDM4ETDP1GAA
SCHEMBL10660674 0.82 KDM4E (0.34) TSHRKDM4ETDP1
SCHEMBL10660476 0.82 KDM4E (0.34) TSHRKDM4ETDP1
SCHEMBL7120350 0.82 KDM4E (0.34) TSHRKDM4ETDP1
Ammonia Solution, Strong SCHEMBL11337856 0.81 KDM4E (0.36) TSHRKDM4ETDP1
SCHEMBL10657546 0.79 KDM4E (0.35) TSHRKDM4ETDP1
SCHEMBL29241367 0.79 KDM4E (0.39) TSHRKDM4ETDP1
SCHEMBL14054153 0.74 KDM4E (0.39) TSHRKDM4ETDP1
SCHEMBL10784796 0.73 KDM4E (0.35) TSHRKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009140334-A2 FOAMABLE COMPOSITIONS FOR DENTAL COATINGS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-11-19 WO disclosed
US-20080305457-A1 Methods of Applying Dental Agents to Dental Surfaces and Polymer Compositions 3M INNOVATIVE PROPERTIES COMPANY 2008-12-11 US disclosed
US-20080299520-A1 Foamable Dental Compositions and Methods 3M INNOVATIVE PROPERITES COMPANY 2008-12-04 US disclosed
EP-1968478-A1 METHODS OF APPLYING DENTAL AGENTS TO DENTAL SURFACES AND POLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2008-09-17 EP disclosed
EP-1968526-A1 FOAMABLE DENTAL COMPOSITIONS AND METHODS 3M Innovative Properties Company (US) 2008-09-17 EP disclosed
WO-2007079170-A1 METHODS OF APPLYING DENTAL AGENTS TO DENTAL SURFACES AND POLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-12 WO disclosed
WO-2007079069-A1 FOAMABLE DENTAL COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-12 WO disclosed
US-20040247534-A1 Foamable fluoride gel compositions and methods of treatment using the same SULTAN DENTAL PRODUCTS, LTD 2004-12-09 US disclosed
US-6251369-B1 DENTAL FLUORIDE FOAMS AND EMULSIFIERS SULTAN DENTAL PRODUCTS, INC. 2001-06-26 US disclosed
US-5824289-A CONTAINING EMULSIFIER, EMULSION STABILIZER, SURFACTANT SULTAN DENTAL PRODUCTS (US) 1998-10-20 US disclosed
US-5071637-A Dental therapy; water, dental fluoride, hydrofluoric acid, eth oxylated polyoxypropylene adduct and phosphoric acid PELLICO MICHAEL A (US) 1991-12-10 US disclosed
US-4770634-A DENTISTRY LACLEDE, INC. 1988-09-13 US disclosed