SCHEMBL4352525

SCHEMBL4352525

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(N)=O

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 16/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352522 1.00 GRPR (0.67) GRPR
SCHEMBL31738530 0.96 GRPR (0.64) GRPR
SCHEMBL1413932 0.96 GRPR (0.68) GRPR
SCHEMBL1413933 0.96 GRPR (0.68) GRPR
SCHEMBL19102240 0.95 GRPR (0.69) GRPR
SCHEMBL16508339 0.95 GRPR (0.69) GRPR
SCHEMBL4353652 0.95 GRPR (0.62) GRPR
SCHEMBL4353658 0.95 GRPR (0.62) GRPR
SCHEMBL5350846 0.94 GRPR (0.66) GRPR
SCHEMBL4344249 0.92 GRPR (0.69) GRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3582761-B1 METHODS AND COMPOSITIONS FOR VAULT NANOPARTICLE IMMOBILIZATION OF THERAPEUTIC MOLECULES AND FOR VAULT TARGETING AUKERA INC (US) 2022-04-20 — — EP disclosed
EP-3568694-B1 TARGETED DOXORUBICIN-GOLD NANOCONJUGATES FOR TUMOR THERAPY UNIV MISSOURI (US) 2022-02-16 — — EP disclosed
WO-2009143101-A2 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2009-11-26 — — WO disclosed
WO-2007095443-A2 GASTRIN RELEASING PEPTIDE COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2007-08-23 — — WO disclosed
EP-1583564-A4 IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS BRACCO IMAGING SPA (IT) 2007-06-13 — — EP disclosed
EP-1583564-A2 IMPROVED LINKERS FOR PHARMACEUTICAL COMPOUNDS Bracco Imaging, S.P.A. (IT) 2005-10-12 — — EP disclosed
WO-2004062574-A9 IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS BRACCO IMAGING SPA (IT) 2005-05-26 — — WO disclosed
WO-2004062574-A2 IMPROVED LINKERS FOR RADIOPHARMACEUTICAL COMPOUNDS BRACCO IMAGING S.P.A. (IT) 2004-07-29 — — WO disclosed
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