⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874115 | 0.82 | — | — | |
| SCHEMBL8168776 | 0.80 | — | — | |
| SCHEMBL167808 | 0.73 | — | — | |
| SCHEMBL283973 | 0.73 | — | — | |
| SCHEMBL2160600 | 0.73 | — | — | |
| SCHEMBL23069504 | 0.71 | — | — | |
| SCHEMBL16288471 | 0.71 | — | — | |
| SCHEMBL2122173 | 0.71 | — | — | |
| SCHEMBL2122168 | 0.71 | — | — | |
| SCHEMBL8011703 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324809-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS AND USES THEREOF | SALZMAN GROUP LTD (IL) | 2022-10-13 | — | — | US | disclosed |
| EP-4025300-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | Salzman Group Ltd. (IL) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021044413-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | SALZMAN GROUP LTD. (IL) | 2021-03-11 | — | — | WO | disclosed |
| US-20090030220-A1 | Transparent desiccating agent | DYNIC CORPORATION (JP) | 2009-01-29 | — | — | US | disclosed |