SCHEMBL435319

SCHEMBL435319

NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 7/20 0.62
▸ NAALAD2 Q9Y3Q0 4/20 0.62
▸ RIMKLA Q8IXN7 1/20 0.62
▸ DPP4 P27487 1/20 0.57
▸ DPP8 Q6V1X1 1/20 0.57
▸ DPP9 Q86TI2 1/20 0.57
▸ GRM8 O00222 1/20 0.57
▸ GRM6 O15303 1/20 0.57
▸ GRIN2D O15399 1/20 0.57
▸ GRIN3B O60391 1/20 0.57
▸ GSR P00390 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ GRIK1 P39086 1/20 0.57
▸ GRM5 P41594 1/20 0.57
▸ GRIA1 P42261 1/20 0.57
▸ GRIA2 P42262 1/20 0.57
▸ GRIA3 P42263 1/20 0.57
▸ SLC1A3 P43003 1/20 0.57
▸ SLC1A2 P43004 1/20 0.57
▸ SLC1A1 P43005 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2710756 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL27956852 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL8382463 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL435318 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL7923681 1.00 FOLH1 (0.62) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL28486006 0.98 FOLH1 (0.60) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL28486008 0.98 FOLH1 (0.60) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL22111146 0.96 FOLH1 (0.58) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL20739235 0.96 FOLH1 (0.58) FOLH1NAALAD2RIMKLADPP4DPP8
SCHEMBL20739236 0.96 FOLH1 (0.58) FOLH1NAALAD2RIMKLADPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 — — EP claimed
US-20230410977-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES 2023-12-21 — — US claimed
CN-114965800-A Renal clear cell carcinoma biomarker and application thereof in early screening 山西医科大学 2022-08-30 — — CN claimed
WO-2022140565-A1 METHODS AND MATERIALS FOR ASSESSING RADIATION EXPOSURE NUTECH VENTURES (US) 2022-06-30 — — WO claimed
US-20160282351-A1 SALIVARY BIOMARKERS FOR CANCERS, METHODS AND DEVICES FOR ASSAYING THE SAME, AND METHODS FOR DETERMINING SALIVARY BIOMARKERS FOR CANCERS SALIVATECH CO., LTD. (JP) 2016-09-29 — — US claimed
EP-3064940-A1 SALIVARY BIOMARKER FOR CANCER, METHOD AND DEVICE FOR ASSAYING SAME, AND METHOD FOR DETERMINING SALIVARY BIOMARKER FOR CANCER Salivatech Co., Ltd. (JP) 2016-09-07 — — EP claimed
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 — — EP claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 — — WO claimed
WO-2012010851-A1 CAPILLARY ELECTROPHORESIS OF CARBOHYDRATES CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-01-26 — — WO claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 — — EP disclosed
EP-3806661-B1 USE OF ANTAGONISTS OF T2R54 FIRMENICH INCORPORATED (US) 2025-07-02 — — EP disclosed
EP-4566459-A2 ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF Firmenich Incorporated (US) 2025-06-11 — — EP disclosed
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof FIRMENICH INCORPORATED (US) 2025-05-13 — — US disclosed
WO-2025038709-A1 METHODS OF FORMING RADIOPAQUE PEPTIDES AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-02-20 — — WO disclosed
EP-0826766-A2 Wash composition Ajinomoto Co., Inc. (JP) 1998-03-04 — — EP disclosed
US-5356805-A Gamma-polyglutamate hydrolase MEIJI SEIKA KAISHA, LTD. (JP) 1994-10-18 — — US disclosed
EP-0559175-A2 gamma-Polyglutamate hydrolase and process for producing same MEIJI SEIKA KAISHA LTD. (JP) 1993-09-08 — — EP disclosed
EP-0232717-B1 ANTIBODY SPECIFIC TO LOW-MOLECULAR WEIGHT SUBSTANCE AND METHOD OF PRODUCING THE SAME BY USING COLLOIDAL METAL PARTICLES AS CARRIER Sadao Shiosaka (CA) 1993-04-14 — — EP disclosed
US-5112606-A METHOD OF PRODUCING ANTIBODIES USING COLLOIDAL METAL AS CARRIER SHIOSAKA SADAO (CA) 1992-05-12 — — US disclosed
EP-0232717-A2 Antibody specific to low-molecular weight substance and method of producing the same by using colloidal metal particles as carrier Sadao Shiosaka (CA) 1987-08-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295396-B2 Antagonists of T2R54 and compositions and uses thereof TAS2R50, TAS2R30, TAS2R60 FOLH1 1173/4885NAALAD2 1629/4885RIMKLA 989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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