Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 17/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034121 | 0.87 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL4205287 | 0.87 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794879 | 0.84 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL4033728 | 0.84 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL4033734 | 0.84 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13793390 | 0.83 | MCHR1 (0.62) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795816 | 0.83 | MCHR1 (0.62) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL4033890 | 0.82 | MCHR1 (0.52) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL4033886 | 0.82 | MCHR1 (0.52) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| Trifluoroacetic Acid SCHEMBL3938784 | 0.81 | MCHR1 (0.62) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611109-A4 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1611109-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087680-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |