Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16481376 | 0.93 | SMN1; SMN2 (0.37) | SMN1; SMN2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL14576619 | 0.93 | CTNNB1 (0.38) | SMN1; SMN2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL18946020 | 0.84 | CTNNB1 (0.41) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL17086606 | 0.81 | NPC1 (0.38) | DYRK1ADYRK1BPKMMAOBPRKCI | |
| SCHEMBL17206884 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDKCNH2PKMMAOB | |
| SCHEMBL9966856 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDKCNH2PKMMAOB | |
| SCHEMBL25209057 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL12316637 | 0.78 | AHR (0.45) | SMN1; SMN2CTNNB1WNT3ACLK1DYRK1A | |
| SCHEMBL13954294 | 0.78 | CTNNB1 (0.41) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL30888514 | 0.78 | CTNNB1 (0.38) | SMN1; SMN2CTNNB1WNT3ACLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032552-B1 | Mesogenic compounds, liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| EP-2032552-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147516-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2007-12-27 | — | — | WO | disclosed |