Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354327 | 1.00 | SRD5A2 (0.52) | SRD5A2CYSLTR2CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL2893402 | 0.87 | CA12 (0.49) | CYSLTR2CYSLTR1ALDH1A1KCNH2GSK3B | |
| SCHEMBL2893403 | 0.87 | CA12 (0.49) | CYSLTR2CYSLTR1ALDH1A1KCNH2GSK3B | |
| SCHEMBL7742884 | 0.80 | KDM4E (0.65) | SRD5A2CYSLTR2CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL7742881 | 0.80 | KDM4E (0.65) | SRD5A2CYSLTR2CYSLTR1KDM4EALDH1A1 | |
| SCHEMBL14021653 | 0.78 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1KCNH2FFAR1 | |
| SCHEMBL2894245 | 0.77 | KCNH2 (0.60) | CYSLTR2CYSLTR1KCNH2PDE5AMRGPRX4 | |
| SCHEMBL4509884 | 0.76 | PPARA (0.65) | SRD5A2GSK3BBACE1FFAR1 | |
| SCHEMBL4509890 | 0.76 | PPARA (0.65) | SRD5A2GSK3BBACE1FFAR1 | |
| SCHEMBL1006525 | 0.76 | SRD5A2 (0.84) | SRD5A2ALDH1A1PKMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098517-A1 | NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-09 | — | — | EP | disclosed |