Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348841 | 0.86 | MEN1 (0.57) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL15786287 | 0.84 | MEN1 (0.76) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL4350046 | 0.84 | MEN1 (0.49) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL4347321 | 0.83 | P2RY1 (0.61) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL4348031 | 0.81 | MAOB (0.64) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL4342271 | 0.81 | KMT2A (0.53) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29555610 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL4353624 | 0.81 | P2RY1 (0.68) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL29556187 | 0.81 | MEN1 (0.61) | MEN1KMT2AMAPTRAB9ANPSR1 | |
| SCHEMBL4345397 | 0.79 | TRPV1 (0.58) | MEN1KMT2AMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |
| CN-1701061-A | Novel compounds for inhibiting rotamase enzymes and uses thereof | JERINI AG (DE) | 2005-11-23 | — | — | CN | claimed |
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | disclosed |