Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743236 | 1.00 | PDE4A (0.52) | PDE4AALDH1A1PDE7AGAACYP1A2 | |
| SCHEMBL1715942 | 0.97 | — | — | |
| SCHEMBL1716067 | 0.92 | — | — | |
| SCHEMBL3066022 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL20594080 | 0.83 | — | — | |
| SCHEMBL10757200 | 0.78 | PDE4A (0.45) | PDE4AALDH1A1PDE7AGAACYP1A2 | |
| SCHEMBL9806561 | 0.78 | PDE4A (0.45) | PDE4AALDH1A1PDE7AGAACYP1A2 | |
| SCHEMBL15461483 | 0.77 | PDE4A (0.46) | PDE4AALDH1A1PDE7AGAACYP1A2 | |
| SCHEMBL13345927 | 0.75 | PDE4A (0.32) | PDE4AALDH1A1 | |
| SCHEMBL8749789 | 0.75 | PDE4A (0.37) | PDE4APDE7AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |