SCHEMBL4356378

SCHEMBL4356378

CCCCCOC1C=CCC=C1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 0.44
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 3/20 0.32
MAPK1 P28482 2/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
RECQL P46063 2/20 0.31
GLA P06280 1/20 0.31
HPGD P15428 1/20 0.31
EPHX2 P34913 1/20 0.31
BLM P54132 1/20 0.31
LMNA P02545 1/20 0.31
PPARG P37231 2/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4352954 0.98 GBA1 (0.47) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL4352560 0.98 GBA1 (0.47) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL4351010 0.98 GBA1 (0.47) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL4352574 0.98 GBA1 (0.47) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL4349272 0.98 GBA1 (0.47) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL4356382 0.94 GBA1 (0.36) GBA1
SCHEMBL4357434 0.85
SCHEMBL6519982 0.84 GBA1 (0.52) GBA1ALDH1A1TSHRMAPK1TP53
SCHEMBL6526191 0.82 GBA1 (0.56) GBA1ALDH1A1TDP1TSHRMAPK1
SCHEMBL6525923 0.82 GBA1 (0.56) GBA1ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487071-B2 Polyether polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-16 US disclosed
US-20110065889-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed
WO-2009142094-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-26 WO disclosed