SCHEMBL4358934

SCHEMBL4358934

O=S(=O)(O)Cc1cc(S(=O)(=O)c2ccc(Cl)c(CS(=O)(=O)O)c2)ccc1Cl.[Na]

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 3/20 0.38
HSD11B1 P28845 1/20 0.37
KMT2A Q03164 2/20 0.37
GAA P10253 2/20 0.36
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 2/20 0.35
FLT1 P17948 2/20 0.35
FLT4 P35916 2/20 0.35
KDR P35968 2/20 0.35
SLC16A1 P53985 1/20 0.35
NAMPT P43490 1/20 0.35
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069820 1.00 POLB (0.41) POLBMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL14395741 0.93 POLB (0.37) POLBMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL14369294 0.83 POLB (0.31) POLBSLC16A1
SCHEMBL4358933 0.83 MAPK1 (0.40) POLBMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL13321612 0.81 CYP3A4 (0.41) POLBALDH1A1CYP3A4MAPTKMT2A
SCHEMBL14369305 0.80 POLB (0.37) POLBMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL27476142 0.79 FLT1 (0.40) POLBALDH1A1CYP3A4MAPTKMT2A
SCHEMBL27536511 0.79 FLT1 (0.40) POLBALDH1A1CYP3A4MAPTKMT2A
SCHEMBL27858505 0.79 FLT1 (0.40) POLBMAPK1ALDH1A1CYP3A4MAPT
SCHEMBL27474700 0.79 FLT1 (0.40) POLBALDH1A1CYP3A4MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed