⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43592 | 1.00 | — | — | |
| SCHEMBL11264582 | 1.00 | — | — | |
| SCHEMBL1114099 | 0.85 | — | — | |
| SCHEMBL1114100 | 0.85 | — | — | |
| SCHEMBL11474234 | 0.85 | — | — | |
| SCHEMBL8648395 | 0.85 | — | — | |
| SCHEMBL8787 | 0.78 | — | — | |
| SCHEMBL2518190 | 0.78 | — | — | |
| SCHEMBL7361807 | 0.78 | — | — | |
| SCHEMBL6641066 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338316-A | PROSTAGLANDIN F SERIES ANALOGUES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-06 | — | — | US | claimed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | claimed |
| US-12024595-B2 | Polymer composition | BASF SE (DE) | 2024-07-02 | — | — | US | disclosed |
| US-20240174664-A1 | BICYCLIC AMINES AS CDK2 INHIBITORS | INCYTE CORPORATION | 2024-05-30 | — | — | US | disclosed |
| WO-2024107686-A1 | MACROCYCLIC KRAS INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-11981671-B2 | Bicyclic pyrazolyl amines as CDK2 inhibitors | INCYTE CORPORATION (US) | 2024-05-14 | — | — | US | disclosed |
| US-11976073-B2 | Bicyclic amines as CDK2 inhibitors | INCYTE CORPORATION (US) | 2024-05-07 | — | — | US | disclosed |
| US-11912722-B2 | Tricyclic heteroaryl compounds as sting activators | INCYTE CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-11866432-B2 | Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors | INCYTE CORPORATION (US) | 2024-01-09 | — | — | US | disclosed |
| WO-2023250430-A1 | BICYCLIC AMINE CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-12-28 | — | — | WO | disclosed |
| US-4590268-A | HALOACYLATION WITH PHOSGENE, AMINATION | CIBA-GEIGY CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |
| US-4584265-A | TRIAZINE COMPOUNDS SUBSTITUTED WITH STERICALLY HINDERED PHENOL=ANDPOLYALKYLPIPERIDINE GROUPS | CIBA-GEIGY AG (CH) | 1986-04-22 | — | — | US | disclosed |
| US-4560709-A | CONTAINING DUAL CATALYST OF AROMATIC IODONIUM SALT AND AROMATIC OXY KETONE | CIBA GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| US-4558131-A | PHOTOSTABILIZERS | CIBA-GEIGY AG (CH) | 1985-12-10 | — | — | US | disclosed |
| US-4556714-A | LIGHT STABILIZER FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |
| US-4540732-A | LUBRICANT AND POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| US-4338316-A | PROSTAGLANDIN F SERIES ANALOGUES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | disclosed |
| EP-0010360-A1 | Prostane derivatives, processes for their preparation and their pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |