SCHEMBL4359241

SCHEMBL4359241

NC=NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL834860 1.00
SCHEMBL4891353 1.00
SCHEMBL31765 0.62
SCHEMBL14174692 0.62
SCHEMBL8499110 0.62
SCHEMBL1067731 0.62
SCHEMBL3960206 0.59
SCHEMBL18520975 0.59
SCHEMBL16327144 0.59
SCHEMBL9410899 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214984-A1 COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2025-07-03 US disclosed
EP-4146645-B1 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF ONO PHARMACEUTICAL CO (JP) 2025-06-25 EP disclosed
CN-120158862-A Knitted component with foam surface features 耐克创新有限合伙公司 2025-06-17 CN disclosed
US-12269817-B2 Compound having KDM5 inhibitory activity and pharmaceutical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2025-04-08 US disclosed
CN-119523226-A Shoe upper for article of footwear and method of manufacturing same 耐克创新有限合伙公司 2025-02-28 CN disclosed
CN-114729480-B Knitted component with foam surface features 耐克创新有限合伙公司 2025-01-03 CN disclosed
EP-4471027-A1 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF ONO Pharmaceutical Co., Ltd. (JP) 2024-12-04 EP disclosed
CN-114729478-B Shoe upper for article of footwear and method of manufacturing same 耐克创新有限合伙公司 2024-12-03 CN disclosed
CN-118854528-A Expandable yarns, textiles and articles incorporating the same, and processes for making the same 耐克创新有限合伙公司 2024-10-29 CN disclosed
CN-114729479-B Expandable yarns, textiles and articles incorporating the same, and processes for making the same 耐克创新有限合伙公司 2024-07-05 CN disclosed
US-20170129880-A1 FACTOR IXa INHIBITORS MERCK SHARP & DOHME LLC 2017-05-11 US disclosed
EP-3131896-A1 FACTOR IXA INHIBITORS Merck Sharp & Dohme Corp. (US) 2017-02-22 EP disclosed
EP-3131897-A1 FACTOR IXA INHIBITORS Merck Sharp & Dohme Corp. (US) 2017-02-22 EP disclosed
US-20170027916-A1 FACTOR IXa INHIBITORS MERCK SHARP & DOHME CORP. (US) 2017-02-02 US disclosed
WO-2015160634-A1 FACTOR IXA INHIBITORS MERCK SHARP & DOHME CORP. (US) 2015-10-22 WO disclosed
WO-2015160636-A1 FACTOR IXA INHIBITORS MERCK SHARP & DOHME CORP. (US) 2015-10-22 WO disclosed
US-20090023826-A1 CROSSLINKED POLYOLEFIN RESIN FOAM TORAY INDUSTRIES, INC. (JP) 2009-01-22 US disclosed
US-20080267942-A1 BENZAZEPIN-2(1H)-ONE DERIVATIVES PFIZER LIMITED (GB) 2008-10-30 US disclosed
EP-1882715-A1 CROSSLINKED POLYOLEFIN RESIN FOAM TORAY INDUSTRIES, INC. (JP) 2008-01-30 EP disclosed
EP-1151853-A1 EASILY DELAMINATABLE LAMINATE AND RESIN COMPOSITION FOR USE THEREIN Sumitomo Chemical Company, Limited (JP) 2001-11-07 EP disclosed