Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 14/20 | 0.69 |
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358408 | 0.92 | AVPR1A (0.72) | AVPR1AOXTRCNR1AVPR2CNR2 | |
| SCHEMBL4356439 | 0.85 | AVPR1A (0.75) | AVPR1AOXTRCNR1AVPR2CNR2 | |
| SCHEMBL4356502 | 0.85 | AVPR1A (0.77) | AVPR1AOXTRAVPR2CNR2HRH3 | |
| SCHEMBL4359918 | 0.85 | AVPR1A (0.81) | AVPR1AOXTRAVPR2HRH3 | |
| SCHEMBL4359922 | 0.85 | AVPR1A (0.81) | AVPR1AOXTRAVPR2HRH3 | |
| SCHEMBL4364334 | 0.84 | AVPR1A (0.80) | AVPR1AOXTRCNR1AVPR2CNR2 | |
| SCHEMBL4356204 | 0.84 | AVPR1A (0.80) | AVPR1AOXTRAVPR2HRH3 | |
| SCHEMBL4356199 | 0.84 | AVPR1A (0.80) | AVPR1AOXTRAVPR2HRH3 | |
| SCHEMBL4355304 | 0.83 | AVPR1A (0.73) | AVPR1AOXTRAVPR2CNR2 | |
| SCHEMBL4355912 | 0.83 | AVPR1A (0.78) | AVPR1AOXTRAVPR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904477-B1 | INDOL-3-CARBONYL-SPIRO-PIPERIDINE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-01-21 | — | — | EP | claimed |