Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464770 | 0.83 | HRH3 (0.69) | HRH3KCNH2ADRA1A | |
| SCHEMBL4469611 | 0.82 | HRH3 (0.77) | HRH3KCNH2 | |
| SCHEMBL4484422 | 0.82 | HRH3 (0.70) | HRH3KCNH2ADRA1A | |
| SCHEMBL4474622 | 0.81 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL502075 | 0.81 | HRH3 (0.81) | HRH3KCNH2 | |
| SCHEMBL502213 | 0.81 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL4478203 | 0.80 | HRH3 (0.74) | HRH3KCNH2 | |
| SCHEMBL502298 | 0.80 | HRH3 (0.78) | HRH3KCNH2ADRA1A | |
| SCHEMBL4468136 | 0.80 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL4468499 | 0.80 | HRH3 (0.77) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010519-A2 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007120655-A2 | SUBSTITUTED IMIDAZOLE 4-CARBOXAMIDES AS CHOLECYSTOKININ-1 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-10-25 | — | — | WO | disclosed |