Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 18/20 | 0.70 |
| ▸ | OXTR | P30559 | 1/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359636 | 1.00 | AVPR1A (0.70) | AVPR1AOXTRAVPR2SPR | |
| SCHEMBL13603015 | 0.84 | AVPR1A (0.69) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359209 | 0.82 | AVPR1A (0.82) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359918 | 0.82 | AVPR1A (0.81) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359922 | 0.82 | AVPR1A (0.81) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359207 | 0.82 | AVPR1A (0.82) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4358542 | 0.82 | AVPR1A (1.00) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4357766 | 0.82 | AVPR1A (1.00) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4357768 | 0.82 | AVPR1A (1.00) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359001 | 0.81 | AVPR1A (0.73) | AVPR1AOXTRAVPR2SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904477-B1 | INDOL-3-CARBONYL-SPIRO-PIPERIDINE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-01-21 | — | — | EP | disclosed |