⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4359998 | 1.00 | — | — | |
| SCHEMBL4361308 | 0.86 | — | — | |
| SCHEMBL1878200 | 0.86 | — | — | |
| SCHEMBL6862827 | 0.84 | HCAR2 (0.33) | — | |
| SCHEMBL6862617 | 0.84 | HCAR2 (0.33) | — | |
| SCHEMBL27894234 | 0.82 | HCAR2 (0.35) | — | |
| SCHEMBL27759852 | 0.82 | HCAR2 (0.35) | — | |
| SCHEMBL27957601 | 0.82 | HCAR2 (0.35) | — | |
| SCHEMBL248098 | 0.79 | — | — | |
| SCHEMBL1830146 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580403-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-02-28 | — | — | US | claimed |
| US-9255081-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2016-02-09 | — | — | US | claimed |
| US-20160031848-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC | 2016-02-04 | — | — | US | claimed |
| US-7619084-B2 | Reacting an acrylonitrile, ammonia and alkyl orthoformate in an ammonia-isopropyl alcoholsolution under stirring at 145 degrees C. for 12 hours; nonteratogenicity, nontoxic; simplification; industrial scale; chemical intermediates; drugs; agricultural chemicals | UBE INDUSTRIES, LTD. (JP) | 2009-11-17 | — | — | US | claimed |
| US-20080045712-A1 | Process for Preparing 4-Aminopyrimidine Compound | UBE INDUSTRIES, LTD. (JP) | 2008-02-21 | — | — | US | claimed |
| CN-101048385-A | Process for producing 4-aminopyrimidine compound | UBE INDUSTRIES (JP) | 2007-10-03 | — | — | CN | claimed |
| US-10035786-B2 | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180030029-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2018-02-01 | — | — | US | disclosed |
| US-9840490-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-12-12 | — | — | US | disclosed |
| EP-3174856-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20170101393-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2017-04-13 | — | — | US | disclosed |
| US-9580403-B2 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160152593-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-06-02 | — | — | US | disclosed |
| US-9255081-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2016-02-09 | — | — | US | disclosed |
| WO-2016018442-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| US-20160031848-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC | 2016-02-04 | — | — | US | disclosed |
| US-9029555-B1 | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine | DOW AGROSCIENCES LLC (US) | 2015-05-12 | — | — | US | disclosed |
| EP-0018473-B1 | PROCESS FOR THE PREPARATION OF BETA-ALKOXY-ACRYLONITRILES, 3-AMINO-ACRYLONITRILES AND 2-CYANO-VINYL ESTERS | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| US-4319024-A | ALKYLATION | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| EP-0018473-A1 | Process for the preparation of beta-alkoxy-acrylonitriles, 3-amino-acrylonitriles and 2-cyano-vinyl esters | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1980-11-12 | — | — | EP | disclosed |