Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.68 |
| ▸ | PPARG | P37231 | 8/20 | 0.50 |
| ▸ | PPARA | Q07869 | 8/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355858 | 0.87 | MDM2 (0.88) | MDM2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7037701 | 0.87 | MDM2 (0.88) | MDM2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL6712771 | 0.83 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL10988389 | 0.83 | MDM2 (0.53) | MDM2PPARGPPARACES2CES1 | |
| Chlorobenzene SCHEMBL27609157 | 0.82 | MDM2 (0.67) | MDM2PPARGPPARACES2CES1 | |
| SCHEMBL3657476 | 0.81 | SLC7A5 (0.53) | MDM2PPARGPPARACES2CES1 | |
| SCHEMBL11307784 | 0.81 | MDM2 (0.51) | MDM2PPARGPPARACES2CES1 | |
| SCHEMBL11713368 | 0.81 | MDM2 (1.00) | MDM2CES2CES1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1249125 | 0.80 | SLC7A5 (0.51) | MDM2PPARGPPARACES2CES1 | |
| SCHEMBL5751703 | 0.79 | MDM2 (0.62) | MDM2PPARGPPARACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072510-A1 | Crystalline form of azelastine | ESTEVE QUIMICA, S.A. (ES) | 2009-06-24 | — | — | EP | disclosed |