Coumaric Acid

Coumaric Acid

SCHEMBL43601

O=C(O)C=Cc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 1.00
TYR P14679 3/20 1.00
AKR1B10 O60218 3/20 1.00
AKR1B1 P15121 3/20 1.00
CA12 O43570 3/20 1.00
CA1 P00915 3/20 1.00
CA2 P00918 3/20 1.00
CA7 P43166 3/20 1.00
CA9 Q16790 3/20 1.00
CA14 Q9ULX7 3/20 1.00
ESR2 Q92731 3/20 1.00
HCAR2 Q8TDS4 2/20 1.00
PKM P14618 2/20 1.00
CA3 P07451 2/20 1.00
CA4 P22748 2/20 1.00
CA6 P23280 2/20 1.00
DPP4 P27487 2/20 1.00
CA5A P35218 2/20 1.00
CA5B Q9Y2D0 2/20 1.00
F3 P13726 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumaric Acid SCHEMBL6333102 1.00 ESR1 (1.00) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL39106 1.00 ESR1 (1.00) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL434720 1.00 ESR1 (1.00) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL6333097 1.00 ESR1 (1.00) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL20702657 1.00 ESR1 (1.00) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL6328280 0.98 ESR1 (0.95) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL1221500 0.98 ESR1 (0.95) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL7871865 0.98 ESR1 (0.95) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL7040450 0.98 ESR1 (0.95) ESR1TYRAKR1B10AKR1B1CA12
Coumaric Acid SCHEMBL5606477 0.98 ESR1 (0.95) ESR1TYRAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 34800 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848462-B1 BAICALEIN- AND SCUTELLAREIN-SYNTHESIZING MICROORGANISM, PREPARATION METHOD, AND APPLICATIONS THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2026-05-27 EP claimed
EP-4747367-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES Symrise AG (DE) 2026-05-27 EP claimed
CN-122074481-A Preparation method and application of p-coumaric acid modified chlorantraniliprole-loaded MOF nano pesticide 2026-05-26 CN claimed
US-12637656-B2 Recombinant yeast capable of producing caffeic acid and/or ferulic acid ABOLIS BIOTECHNOLOGIES (FR) 2026-05-26 US claimed
CN-122075458-A New application of p-hydroxy cinnamic acid 2026-05-26 CN claimed
CN-122071832-A Polyethylene non-woven fabric and preparation method, preparation device and application thereof 中国石油化工股份有限公司 2026-05-22 CN claimed
US-20260137644-A1 COMPOSITIONS INCLUDING CAFFEIC ACID PHENETHYL ESTER XMK THERAPEUTICS INC. (CA) 2026-05-21 US claimed
EP-4378448-B1 EXTRACT OF FLOWERS, LEAVES AND/OR SEED PODS OF IMPATIENS AND LEAVES OF PANDANUS, IN DRIED AND LIQUID FORM, A METHOD OF ITS OBTAINING AND USE THEREOF PBCLABS SP Z O O (PL) 2026-05-20 EP claimed
US-12630849-B2 Method for producing polyphenol-containing composition TORAY INDUSTRIES, INC. (JP) 2026-05-19 US claimed
CN-118252866-B Method for extracting and purifying Phellinus linteus fruiting body phenols in series and application of Phellinus linteus fruiting body phenols in uric acid regulation 湖北省农业科学院农产品加工与核农技术研究所 2026-05-19 CN claimed
EP-0087161-A2 Isopropylmyristate 4-alkyl-2,6-(bis-tert-butyl)-phenol medicament Key Pharmaceuticals, Inc. (US) 1983-08-31 EP claimed
US-4370416-A CULTIVATION OF ASPERGILLUS OR BOTRYTIS KIKKOMAN CORPORATION (JP) 1983-01-25 US claimed
US-4340671-A E. coli sensitivity broth MCDONNELL DOUGLAS CORPORATION (US) 1982-07-20 US claimed
US-4302199-A Hair dyeing method THE PROCTER & GAMBLE COMPANY (US) 1981-11-24 US claimed
EP-0039472-A1 Radiation-crosslinkable polyesters and polyesterethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-11 EP claimed
US-4297125-A Tree rooting using synthetic auxins THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1981-10-27 US claimed
US-4284710-A FROM DIEPOXIDE AND AROMATIC UNSATURATED DICARBOXYLIC ACID OR HYDROXY ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-18 US claimed
US-4072572-A E. coli detection broth for clinical use with automated microbial analyzer MCDONNELL DOUGLAS CORPORATION (US) 1978-02-07 US claimed
US-4000041-A ESCHERICHIA; COUMARIC ACID GROWTH INHIBITER MCDONNELL DOUGLAS CORPORATION (US) 1976-12-28 US claimed
US-3943137-A ANTITUMOR UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) 1976-03-09 US claimed