Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.62 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.58 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669588 | 0.96 | TSHR (0.67) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL13669590 | 0.96 | TSHR (0.67) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL4362716 | 0.96 | TSHR (0.67) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL4366475 | 0.96 | TSHR (0.67) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL11580063 | 0.96 | TSHR (0.67) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL13885677 | 0.95 | GAA (0.73) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL4364442 | 0.94 | TSHR (0.62) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL4360846 | 0.94 | TSHR (0.62) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL11581351 | 0.93 | GAA (0.65) | GAARAB9ATSHRLNPEPCTSL | |
| SCHEMBL4373087 | 0.93 | TSHR (0.61) | GAARAB9ATSHRLNPEPCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | claimed |
| US-9023809-B2 | Phenylalanine dipeptide derivatives, compositions and use thereof | THE KEY LABORATORY OF CHEMISTRY FOR NATURAL PRODUCTS OF GUIZHOU PROVINCE AND CHINESE ACADEMY OF SCIENCES (CN) | 2015-05-05 | — | — | US | disclosed |
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | The Key Lab. Of Chemistry for Natural Products of Guizhou Province and Chinese Acad. of Sciences (CN) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247470-A1 | PHENYLALANINE DIPEPTIDE DERIVATIVES, COMPOSITIONS AND USE THEREOF | DNPEP, PEPD, VIP | GAA 407/4885RAB9A 2865/4885TSHR 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.