Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTRN | P46939 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363580 | 1.00 | UTRN (0.58) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL3717358 | 0.79 | KMT2A (0.53) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL4053461 | 0.79 | UTRN (0.56) | UTRNHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4053466 | 0.79 | UTRN (0.56) | UTRNHDAC6RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3812296 | 0.78 | CYP1A2 (0.51) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL3812306 | 0.78 | CYP1A2 (0.51) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL3812302 | 0.78 | CYP1A2 (0.51) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL28510184 | 0.78 | SNCA (0.64) | UTRNCYP1A2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2243039 | 0.77 | UTRN (0.77) | UTRNCYP1A2AHRHDAC6RAB9A | |
| SCHEMBL3717356 | 0.77 | CYP1A2 (0.50) | UTRNCYP1A2AHRHDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |