Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361524 | 0.82 | EGFR (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4886774 | 0.82 | EGFR (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4887342 | 0.77 | EGFR (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4365493 | 0.77 | EGFR (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL4876145 | 0.75 | MAOB (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4372188 | 0.75 | MAOB (0.38) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL13893467 | 0.75 | FLT3 (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4886302 | 0.72 | MAPT (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4377457 | 0.72 | MAPT (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4369481 | 0.71 | MAPT (0.39) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046536-A1 | HALOGENATED QUINAZOLINYL NITROFURANS AS ANTIBACTERIAL AGENTS | ULYSSES PHARMACEUTICAL PRODUCTS, INC. (CA) | 2009-04-16 | — | — | WO | disclosed |