⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396320 | 0.76 | — | — | |
| SCHEMBL477607 | 0.70 | — | — | |
| SCHEMBL323519 | 0.67 | — | — | |
| SCHEMBL8355042 | 0.67 | — | — | |
| SCHEMBL4606136 | 0.64 | — | — | |
| SCHEMBL18632175 | 0.64 | — | — | |
| SCHEMBL1038851 | 0.63 | — | — | |
| SCHEMBL15402510 | 0.61 | — | — | |
| SCHEMBL17528570 | 0.60 | — | — | |
| Norflurane SCHEMBL6367265 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027309-A1 | GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2017-02-16 | — | — | WO | claimed |
| US-8962608-B2 | Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-02-24 | — | — | US | claimed |
| US-20140243309-A1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-28 | — | — | US | claimed |
| CN-100528881-C | Fluorinated alkyl substituted-thieno[3,4-b]thiophene monomers and polymers therefrom | AIR PROD & CHEM (US) | 2009-08-19 | — | — | CN | claimed |
| US-7572879-B2 | Fluorinated alkyl substituted-thieno[3,4-b]thiophene monomers and polymers therefrom | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-08-11 | — | — | US | claimed |
| US-7432340-B2 | Fluorinated alkyl substituted-thieno[3,4-]thiophene monomers and polymers therefrom | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-10-07 | — | — | US | claimed |
| EP-1728810-B1 | 2-flouroalkyl-thieno[3,4-b]thiophene derivatives and polymers therefrom | AIR PROD & CHEM (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1728810-A1 | 2-flouroalkyl-thieno[3,4-b]thiophene derivatives and polymers therefrom | Air Products and Chemicals, Inc. (US) | 2006-12-06 | — | — | EP | claimed |
| CN-1869038-A | Fluorinated alkyl substituted-thieno[3,4-b]thiophene monomers and polymers therefrom | AIR PROD & CHEM (US) | 2006-11-29 | — | — | CN | claimed |
| US-20060223977-A1 | Fluorinated alkyl substituted-thieno[3,4-b]thiophene monomers and polymers therefrom | SAMSUNG ELECTRONICS CO., LTD (KR) | 2006-10-05 | — | — | US | claimed |
| US-20050209419-A1 | Fluorinated alkyl substituted-thieno[3,4-b]thiophene monomers and polymers therefrom | SAMSUNG ELECTRONICS CO., LTD (KR) | 2005-09-22 | — | — | US | claimed |
| CN-104011010-B | Bisaniline compounds and its manufacture method | 组合化学工业株式会社 | 2017-11-28 | — | — | CN | disclosed |
| EP-2758377-B1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2017-08-02 | — | — | EP | disclosed |
| US-8962608-B2 | Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140243309-A1 | CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-08-28 | — | — | US | disclosed |
| US-6943271-B2 | Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2005-09-13 | — | — | US | disclosed |
| WO-2004056825-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
| US-20040002612-A1 | Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-01-01 | — | — | US | disclosed |
| US-20030232940-A1 | Fluorine-containing polymerizable monomers and polymers, anti-reflection film materials and resist compositions using same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2003-12-18 | — | — | US | disclosed |
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |