⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477814 | 1.00 | — | — | |
| SCHEMBL477798 | 1.00 | — | — | |
| SCHEMBL10822584 | 0.78 | — | — | |
| SCHEMBL1469542 | 0.78 | — | — | |
| SCHEMBL164274 | 0.78 | — | — | |
| SCHEMBL4340365 | 0.78 | — | — | |
| SCHEMBL4591460 | 0.72 | — | — | |
| SCHEMBL16144920 | 0.72 | — | — | |
| SCHEMBL25296 | 0.72 | — | — | |
| SCHEMBL2814 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5990 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064178-A1 | HEXAHYDRO-2H-PYRIDO[2,1-A]ISOQUINOLINE VMAT2 INHIBITORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2024-03-28 | — | — | WO | claimed |
| US-20230365533-A1 | BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2023-11-16 | — | — | US | claimed |
| WO-2023134713-A1 | FUSED AZAHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 南方科技大学 | 2023-07-20 | — | — | WO | claimed |
| EP-4200295-A1 | BICYCLOHEPTANE PYRROLIDINE OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-06-28 | — | — | EP | claimed |
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | claimed |
| CN-115974872-A | Aza-and-ring derivatives, pharmaceutical compositions thereof and uses thereof | 南方科技大学 | 2023-04-18 | — | — | CN | claimed |
| EP-3566863-B1 | PHOTONIC CRYSTAL STRUCTURE AND ANTI-FORGERY COLOR CONVERSION FILM COMPRISING SAME | KOREA RES INST CHEMICAL TECH (KR) | 2023-03-08 | — | — | EP | claimed |
| US-20230065953-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | claimed |
| US-11531150-B2 | Photonic crystal structure and anti-forgery color conversion film comprising same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2022-12-20 | — | — | US | claimed |
| CN-114891013-A | Derivatives of cephalotaxine compounds, preparation method, pharmaceutical composition and application thereof | 南方科技大学 | 2022-08-12 | — | — | CN | claimed |
| WO-2005058328-A1 | TETRAHYDROBENZAZEPINES AND THEIR USE IN THE MODULATION OF THE DOPAMINE D3 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2005-06-30 | — | — | WO | claimed |
| EP-0991658-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999033790-A1 | INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS | NIHON BAYER AGROCHEM K.K. (DE) | 1999-07-08 | — | — | WO | claimed |
| WO-1999031101-A1 | ADENOSINE RECEPTOR ANTAGONISTS WITH IMPROVED BIOACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 1999-06-24 | — | — | WO | claimed |
| WO-1999003879-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | claimed |
| US-5492792-A | OPTICAL CARD OR DISKS; EXCELLENT LIGHT SENSITIVITY WITHIN NEAR INFRARED REGION AND HEAT RESISTANCE; STORE INFORMATIONSAT HIGH DENSITY | CANON KABUSHIKI KAISHA (JP) | 1996-02-20 | — | — | US | claimed |
| US-5206149-A | Reaction of peroxidase, oxidant, luminol and 2-hydroxy-9-fluorenone enhancer; chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1993-04-27 | — | — | US | claimed |
| US-4983596-A | Microbiocides; for treatment of infectious diseases | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-08 | — | — | US | claimed |
| EP-0341557-A1 | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | claimed |
| EP-0120814-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL- AND -TRIAZINYL UREA | CIBA-GEIGY AG (CH) | 1988-07-27 | — | — | EP | claimed |