SCHEMBL4365980

SCHEMBL4365980

CNC1=Nc2ccc(Cl)cc2C(c2ccccc2F)=N[C@H]1CCC(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13862652 0.92
SCHEMBL13862658 0.89
SCHEMBL13862609 0.89 TRPV1 (0.51)
SCHEMBL13862659 0.89
SCHEMBL13862608 0.89 TRPV1 (0.50)
SCHEMBL13862653 0.89 TRPV1 (0.51)
SCHEMBL13862656 0.89 TRPV1 (0.50)
SCHEMBL13862610 0.88
SCHEMBL13862606 0.88
SCHEMBL13862654 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7160880-B1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-01-09 US claimed
EP-1183243-B1 SHORT-ACTING BENZODIAZEPINES CENES LTD (GB) 2006-02-08 EP claimed
EP-1183243-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2002-03-06 EP claimed
WO-2000069836-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2000-11-23 WO claimed
US-7528127-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-05-05 US disclosed
US-7528127-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-05-05 US disclosed
US-7485635-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-02-03 US disclosed
US-7485635-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-02-03 US disclosed
US-7473689-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-01-06 US disclosed
US-7473689-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2009-01-06 US disclosed
US-7435730-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2008-10-14 US disclosed
US-7435730-B2 Short-acting benzodiazepines CENES LIMITED (GB) 2008-10-14 US disclosed
US-20070093475-A1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-04-26 US disclosed
US-20070093475-A1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-04-26 US disclosed
US-20070093475-A1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-04-26 US disclosed
US-7160880-B1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-01-09 US disclosed
US-7160880-B1 Short-acting benzodiazepines CENES LIMITED (GB) 2007-01-09 US disclosed
EP-1183243-B1 SHORT-ACTING BENZODIAZEPINES CENES LTD (GB) 2006-02-08 EP disclosed
EP-1183243-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2002-03-06 EP disclosed
WO-2000069836-A1 SHORT-ACTING BENZODIAZEPINES GLAXO GROUP LIMITED (GB) 2000-11-23 WO disclosed