Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19021085 | 0.87 | MEN1 (0.69) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL4721440 | 0.86 | MEN1 (0.68) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL31681091 | 0.86 | MEN1 (0.68) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL438878 | 0.86 | KMT2A (0.71) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL774503 | 0.85 | MEN1 (0.67) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL440812 | 0.85 | KMT2A (0.70) | KMT2AMEN1NPC1RAB9ALMNA | |
| SCHEMBL440425 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL10126200 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL437697 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL440043 | 0.84 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |