Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439469 | 0.87 | KMT2A (0.67) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL15054185 | 0.86 | KMT2A (0.47) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL436903 | 0.85 | KMT2A (0.65) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL437697 | 0.85 | KMT2A (0.68) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL439981 | 0.84 | HAVCR2 (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL438293 | 0.80 | NPC1 (0.55) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL440533 | 0.80 | KMT2A (0.65) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL437101 | 0.80 | KMT2A (0.65) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL438878 | 0.79 | KMT2A (0.71) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL440812 | 0.78 | KMT2A (0.70) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |