⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725771 | 0.83 | — | — | |
| SCHEMBL126880 | 0.83 | — | — | |
| SCHEMBL28814565 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL7515887 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL27591660 | 0.77 | — | — | |
| SCHEMBL23037778 | 0.77 | — | — | |
| SCHEMBL25173724 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL7515880 | 0.77 | — | — | |
| SCHEMBL9116309 | 0.77 | — | — | |
| SCHEMBL27597958 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021978-A2 | COMPOUNDS CONTAINING CARBABORANE RESIDUES AND THE USE THEREOF IN MEDICINE, ESPECIALLY FOR USE IN TUMOUR THERAPY | UNIVERSITÄT LEIPZIG (DE) | 2009-02-19 | — | — | WO | claimed |
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-115667218-A | Kinase inhibitors | GB005股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-114634447-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114621146-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114605327-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-114591242-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-110283204-B | System and method for preparing methyl phosphite ester by adopting aluminum methyl chloride | 浙江新安化工集团股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113636978-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113603645-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-110283202-B | System and method for preparing methylphosphonite from aluminum methylchloride | 浙江新安化工集团股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-110283205-B | System and method for preparing methylphosphonite | 浙江新安化工集团股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| EP-3028715-A1 | USE OF RAPAMYCIN AS VACCINE ADJUVANT AND PREPARATION METHOD THEREFOR | Institut Pasteur of Shanghai, Chinese Academy of Sciences (CN) | 2016-06-08 | — | — | EP | disclosed |
| WO-2009021978-A2 | COMPOUNDS CONTAINING CARBABORANE RESIDUES AND THE USE THEREOF IN MEDICINE, ESPECIALLY FOR USE IN TUMOUR THERAPY | UNIVERSITÄT LEIPZIG (DE) | 2009-02-19 | — | — | WO | disclosed |
| US-6956072-B1 | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |
| US-6225386-B1 | PHOSPHONIUM SULFONATE AND INORGANIC SULFONATE; DOESN'T ADVERSELY EFFECT NATURAAL HUE AND TRANSPARENCY OF MATERIAL | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0456049-B1 | Process for the preparation of vinylphosphonic acid derivatives | BASF AG (DE) | 1995-02-15 | — | — | EP | disclosed |
| EP-0456049-A1 | Process for the preparation of vinylphosphonic acid derivatives | BASF Aktiengesellschaft (DE) | 1991-11-13 | — | — | EP | disclosed |
| US-4509970-A | Substituted phenylphosphinyloxy- and phosphinylthio-iminocarboxylates useful for the control of weeds | ZOECON CORPORATION (US) | 1985-04-09 | — | — | US | disclosed |