Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326851 | 0.84 | ALOX5AP (0.60) | ALOX5AP | |
| SCHEMBL4328667 | 0.81 | ALOX5AP (0.79) | ALOX5AP | |
| SCHEMBL4312676 | 0.80 | ALOX5AP (0.71) | ALOX5AP | |
| SCHEMBL4057182 | 0.78 | ALOX5AP (0.84) | ALOX5AP | |
| SCHEMBL4315092 | 0.77 | ALOX5AP (1.00) | ALOX5AP | |
| SCHEMBL4326800 | 0.77 | ALOX5AP (0.82) | ALOX5AP | |
| SCHEMBL13750360 | 0.77 | ALOX5AP (0.65) | ALOX5AP | |
| SCHEMBL4050080 | 0.76 | ALOX5AP (1.00) | ALOX5AP | |
| SCHEMBL4321615 | 0.76 | ALOX5AP (0.64) | ALOX5AP | |
| SCHEMBL4060007 | 0.76 | ALOX5AP (0.82) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858513-A4 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1858513-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006098912-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2006-09-21 | — | — | WO | disclosed |