SCHEMBL436768

SCHEMBL436768

CCN(CCCCCCN)c1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
TDP1 Q9NUW8 4/20 1.00
ALDH1A1 P00352 7/20 0.40
HPGD P15428 4/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
CASP1 P29466 3/20 0.40
CASP7 P55210 3/20 0.40
USP2 O75604 1/20 0.40
TSHR P16473 1/20 0.40
RECQL P46063 1/20 0.40
SRC P12931 2/20 0.38
IGLV6-57 P01721 2/20 0.38
AR P10275 4/20 0.36
L3MBTL1 Q9Y468 4/20 0.35
MAPT P10636 4/20 0.35
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 2/20 0.35
GLA P06280 3/20 0.35
CYP3A4 P08684 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421583 1.00 KDM4E (1.00) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL437558 0.99 KDM4E (0.97) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL29394268 0.99 KDM4E (0.97) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL14321770 0.99 KDM4E (0.97) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL19411235 0.94 KDM4E (0.88) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL19692609 0.91 KDM4E (0.84) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL29421600 0.89 KDM4E (0.80) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL3075296 0.89 KDM4E (0.80) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL12208991 0.87 KDM4E (0.78) KDM4ETDP1ALDH1A1HPGDMEN1
SCHEMBL29356118 0.86 KDM4E (0.76) KDM4ETDP1ALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11650203-B2 One-pot biosensor and immunoassay method using the same GIST (Gwangju Institute of Science and Technology) (KR) 2023-05-16 US claimed
US-20210405042-A1 ONE-POT BIOSENSOR AND IMMUNOASSAY METHOD USING THE SAME GIST (Gwangju Institute of Science and Technology) (KR) 2021-12-30 US claimed
US-9663815-B2 Cytosolically-active peroxidases as reporters for microscopy MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-05-30 US claimed
US-20150037829-A1 CYTOSOLICALLY-ACTIVE PEROXIDASES AS REPORTERS FOR MICROSCOPY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-02-05 US claimed
EP-2596119-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Advanced Cell Technology, Inc. (US) 2013-05-29 EP claimed
WO-2013040388-A1 CYTOSOLICALLY-ACTIVE PEROXIDASES AS REPORTERS FOR MICROSCOPY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-03-21 WO claimed
WO-2012012803-A2 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ADVANCED CELL TECHNOLOGY, INC. (US) 2012-01-26 WO claimed
US-7759468-B1 modifying a 6-[N-(6-aminohexyl)-N-ethylamino]-2,3-dihydro-phthalazine-1,4-dione marker to include an amino-terminal carboxymethoxyacetyl tether molecule, and covalently binding the tether molecule to a bacteriophage-derived peptide; suitable for a rapid assay for a bacteria in a complex mixture UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2010-07-20 US claimed
US-6322992-B1 CONTACTING FLUID SAMPLE SUSPECTED OF CONTAINING SPECIFIC BINDING LIGAND WITH AN ANALYTIC ELEMENT CONTAINING VANADIUM BROMOPEROXIDASE-LABELED LIGAND OR ANALOG, AND IMMOBILIZED RECEPTOR THAT BINDS LIGAND OR ANALOG; APPLYING WASH SOLUTION JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. 2001-11-27 US claimed
EP-0848819-B1 ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME ORTHO CLINICAL DIAGNOSTICS INC (US) 2000-04-26 EP claimed
EP-0892855-A1 USE OF VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME FOR CHEMILUMINESCENT SYSTEMS: TEST KITS AND ANALYTICAL METHODS Ortho-Clinical Diagnostics, Inc. (US) 1999-01-27 EP claimed
US-5811253-A Use of vanadium bromoperoxidase as a signal-generating enzyme for chemiluminescent systems: test kits and analytical methods JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1998-09-22 US claimed
EP-0848819-A1 ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME Ortho-Clinical Diagnostics, Inc. (US) 1998-06-24 EP claimed
WO-1997009447-A1 USE OF VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME FOR CHEMILUMINESCENT SYSTEMS: TEST KITS AND ANALYTICAL METHODS JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1997-03-13 WO claimed
WO-1997009619-A1 ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1997-03-13 WO claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US claimed
US-5372931-A Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods EASTMAN KODAK COMPANY (US) 1994-12-13 US claimed
US-5279940-A Containing 2,3-dihydro-1,4-phthalazinedione, cationic surfactant, and 4*-hydroxyacetanilide EASTMAN KODAK COMPANY (US) 1994-01-18 US claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed