SCHEMBL4368658

SCHEMBL4368658

C=CC(=O)OCCCC.O=C1CC1

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.79
HPGD P15428 1/20 0.79
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 1/20 0.57
ATM Q13315 1/20 0.55
HCAR2 Q8TDS4 3/20 0.49
TP53 P04637 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 3/20 0.44
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PRKCA P17252 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5681395 0.89 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1330627 0.89
SCHEMBL11582291 0.89 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1331857 0.89
SCHEMBL15037 0.89
SCHEMBL1493269 0.87 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1160870 0.87 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
Methyl Alcohol SCHEMBL3865866 0.87 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
Ethylene SCHEMBL48332 0.87 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL11582281 0.87 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973609-B1 POLYMER COMPOSITES AND METHODS FOR MAKING AND USING SAME INTEGUMENT TECHNOLOGIES INC (US) 2009-04-15 EP disclosed
US-20080131609-A1 Methods and materials for reducing damage from environmental electromagnetic effects VARGO TERRENCE G 2008-06-05 US disclosed
US-7223312-B2 Methods and materials for reducing damage from environmental electromagnetic effects INTEGUMENT TECHNOLOGIES, INC. (US) 2007-05-29 US disclosed
US-7217754-B2 For use as photo-/electromagnetic- radiation shields/filters, antistatic layers, antifouling coatings, electrodes, in flame/heat retardant materials, construction materials, electrolytic/fuel cells, and optoelectronic devices INTEGUMENT TECHNOLOGIES, INC. (US) 2007-05-15 US disclosed
US-20050150596-A1 Methods and materials for reducing damage from environmental electromagnetic effects VARGO TERRENCE G (US) 2005-07-14 US disclosed
EP-1337373-A4 METHODS AND MATERIALS FOR REDUCING DAMAGE FROM ENVIRONMENTAL ELECTROMAGNETIC EFFECTS INTEGUMENT TECHNOLOGIES INC (US) 2005-01-12 EP disclosed
US-20040019143-A1 For use as photo-/electromagnetic- radiation shields/filters, antistatic layers, antifouling coatings, electrodes, in flame/heat retardant materials, construction materials, electrolytic/fuel cells, and optoelectronic devices INTEGUMENT TECHNOLOGIES, INC. 2004-01-29 US disclosed
EP-1337373-A1 METHODS AND MATERIALS FOR REDUCING DAMAGE FROM ENVIRONMENTAL ELECTROMAGNETIC EFFECTS Integument Technologies, Inc. (US) 2003-08-27 EP disclosed
US-6608129-B1 Inorganic-organic polymer composites; surface properties (e.g., wetability, reactivity, adhesiveness, and physical and chemical toughness); oxidizing agent in the presence of composite; INTEGUMENT TECHNOLOGIES, INC. 2003-08-19 US disclosed
US-6548590-B1 Polymer and inorganic-organic hybrid composites and methods for making and using same INTEGUMENT TECHNOLOGIES, INC. 2003-04-15 US disclosed
US-20020081921-A1 Methods and materials for reducing damage from environmental electromagnetic effects INTEGUMENT TECHNOLOGIES, INC. 2002-06-27 US disclosed
WO-2002024383-A1 METHODS AND MATERIALS FOR REDUCING DAMAGE FROM ENVIRONMENTAL ELECTROMAGNETIC EFFECTS INTEGUMENT TECHNOLOGIES, INC. (US) 2002-03-28 WO disclosed
US-6232386-B1 BLEND WITH FILLER INTEGUMENT TECHNOLOGIES, INC. 2001-05-15 US disclosed
US-5977241-A Polymer and inorganic-organic hybrid composites and methods for making same INTEGUMENT TECHNOLOGIES, INC. (US) 1999-11-02 US disclosed
EP-0662102-B1 PROCESS FOR MAKING POLYMERIC INORGANIC-ORGANIC COMPOSITIONS DU PONT (US) 1997-03-26 EP disclosed
US-5502111-A IMIDIZED ACRYLATE RESIN E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-26 US disclosed
US-5412016-A Interpenetrating polymer networks E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-05-02 US disclosed
EP-0574518-A1 PROCESS FOR MAKING POLYVINYLCHLORIDE COMPOSITIONS HAVING HIGH HEAT DISTORTION TEMPERATURES. DU PONT (US) 1993-12-22 EP disclosed