Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4368707 | 1.00 | DPP4 (0.50) | DPP4 | |
| SCHEMBL4376493 | 0.92 | DPP4 (0.58) | DPP4 | |
| SCHEMBL4376489 | 0.92 | DPP4 (0.58) | DPP4 | |
| SCHEMBL4370416 | 0.74 | DPP4 (0.32) | DPP4 | |
| SCHEMBL4370413 | 0.74 | DPP4 (0.32) | DPP4 | |
| SCHEMBL4368850 | 0.74 | TUBB1 (0.38) | DPP4 | |
| SCHEMBL13581425 | 0.70 | TUBB1 (0.35) | DPP4 | |
| SCHEMBL13682708 | 0.68 | DPP4 (0.47) | DPP4 | |
| SCHEMBL6804633 | 0.68 | DPP4 (0.47) | DPP4 | |
| SCHEMBL16056549 | 0.68 | DPP4 (0.47) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626023-B2 | Compounds for treating tumors | WYETH (US) | 2009-12-01 | — | — | US | disclosed |
| US-20080221181-A1 | COMPOUNDS FOR TREATING TUMORS | WYETH HOLDINGS CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| US-7390910-B2 | Compounds for treating tumors | WYETH (US) | 2008-06-24 | — | — | US | disclosed |
| US-20050037977-A1 | Compounds for treating tumors | WYETH HOLDINGS CORPORATION (US) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221181-A1 | COMPOUNDS FOR TREATING TUMORS | RB1, MRPL9, BCOR | DPP4 4533/4885 |
| US-20050037977-A1 | Compounds for treating tumors | RB1, MRPL9, BCOR | DPP4 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.