Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 15/20 | 0.69 |
| ▸ | OXTR | P30559 | 1/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360808 | 0.91 | AVPR1A (0.69) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4357772 | 0.88 | AVPR1A (0.72) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4358878 | 0.87 | AVPR1A (0.71) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4359158 | 0.87 | AVPR1A (0.69) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4356061 | 0.86 | AVPR1A (0.70) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4359209 | 0.86 | AVPR1A (0.82) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359207 | 0.86 | AVPR1A (0.82) | AVPR1AOXTRAVPR2 | |
| SCHEMBL4359135 | 0.85 | AVPR1A (0.69) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL4359951 | 0.85 | AVPR1A (0.65) | AVPR1AOXTRAVPR2MEN1KMT2A | |
| SCHEMBL13603014 | 0.85 | AVPR1A (0.63) | AVPR1AOXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904477-B1 | INDOL-3-CARBONYL-SPIRO-PIPERIDINE DERIVATIVES AS V1A RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-01-21 | — | — | EP | disclosed |