Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | FABP3 | P05413 | 7/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL3684383 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL9183742 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL11050745 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL9820842 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3137967 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL1194226 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL8006228 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL1194225 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL5146021 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Adipic Acid SCHEMBL3685228 | 0.92 | CA1 (0.58) | CA1FFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563742-B2 | Supported nickel catalysts having high nickel loading and high metal dispersion and methods of making same | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2009-07-21 | — | — | US | disclosed |
| US-20080076660-A1 | Supported Nickel Catalysts Having High Nickel Loading and High Metal Dispersion and Methods of Making Same | HEADWATERS HEAVY OIL, LLC | 2008-03-27 | — | — | US | disclosed |
| WO-2008036743-A2 | SUPPORTED NICKEL CATALYSTS HAVING HIGH NICKEL LOADING AND HIGH METAL DISPERSION AND METHODS OF MAKING SAME | HEADWATERS TECHNOLOGY INNOVATION LLC (US) | 2008-03-27 | — | — | WO | disclosed |
| EP-0279090-B1 | GASOLINE COMPOSITIONS CONTAINING HEXAVALENT MOLYBDENUM | AMOCO CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0279090-A1 | Gasoline compositions containing hexavalent molybdenum | AMOCO CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4647293-A | Gasoline compositions containing hexavalent molybdenum | Magidson, William H. (US) | 1987-03-03 | — | — | US | disclosed |