Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.82 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23573505 | 0.90 | EPHX1 (0.68) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL2131537 | 0.90 | EPHX1 (0.68) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL23573324 | 0.90 | EPHX1 (0.68) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL5145670 | 0.90 | EPHX1 (1.00) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL17875071 | 0.88 | EPHX1 (0.78) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL27735941 | 0.87 | EPHX1 (0.77) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL6631203 | 0.87 | EPHX1 (0.77) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL29067100 | 0.87 | EPHX1 (0.63) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL27258750 | 0.87 | EPHX1 (0.77) | EPHX1EPHX2KMT2AMEN1ACHE | |
| SCHEMBL8538835 | 0.86 | EPHX2 (0.65) | EPHX1EPHX2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487979-B2 | CONSTRUCTS AND METHODS FOR THE REGULATION OF GENE EXPRESSION | BASF PLANT SCIENCE GMBH (DE) | 2018-12-19 | — | — | EP | claimed |
| EP-1487979-B1 | CONSTRUCTS AND METHODS FOR THE REGULATION OF GENE EXPRESSION | BASF PLANT SCIENCE GMBH (DE) | 2009-08-26 | — | — | EP | claimed |
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2021-07-01 | — | — | US | disclosed |
| WO-2015130445-A1 | QUINOLINE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-03 | — | — | WO | disclosed |
| WO-2015130444-A1 | QUINOLINE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2015-09-03 | — | — | WO | disclosed |
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198239-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | ENTPD5, ADORA2A, ENTPD1 | EPHX1 629/4885EPHX2 959/4885KMT2A 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.