Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192481 | 1.00 | SHH (0.64) | SHHMAPK1 | |
| SCHEMBL12507951 | 1.00 | SHH (0.64) | SHHMAPK1 | |
| SCHEMBL2192490 | 1.00 | SHH (0.64) | SHHMAPK1 | |
| SCHEMBL12418076 | 1.00 | SHH (0.64) | SHHMAPK1 | |
| SCHEMBL17497360 | 0.85 | SHH (0.67) | SHH | |
| SCHEMBL17497363 | 0.85 | SHH (0.67) | SHH | |
| SCHEMBL17515410 | 0.83 | SHH (0.60) | SHH | |
| SCHEMBL17497585 | 0.83 | SHH (0.68) | SHH | |
| SCHEMBL17497590 | 0.83 | SHH (0.68) | SHH | |
| SCHEMBL17497507 | 0.82 | SHH (0.60) | SHH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132032-A2 | SONIC HEDGEHOG MODULATORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-10-29 | — | — | WO | disclosed |