Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5934062 | 0.87 | ADORA2A (0.87) | ADORA2A | |
| SCHEMBL5934057 | 0.87 | ADORA2A (0.87) | ADORA2A | |
| SCHEMBL7072690 | 0.81 | ADORA2A (0.88) | ADORA2A | |
| SCHEMBL4380944 | 0.81 | ADORA2A (0.88) | ADORA2A | |
| SCHEMBL4380946 | 0.81 | ADORA2A (0.88) | ADORA2A | |
| SCHEMBL4372964 | 0.81 | ADORA2A (0.78) | ADORA2A | |
| SCHEMBL4376272 | 0.80 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL5969961 | 0.80 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL4376268 | 0.80 | ADORA2A (1.00) | ADORA2A | |
| SCHEMBL13863051 | 0.78 | ADORA2A (0.95) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292604-B1 | 2-AMINOCARBONYL-9H-PURINE DERIVATIVES | PFIZER LTD (GB) | 2009-05-13 | — | — | EP | disclosed |