SCHEMBL4370940

SCHEMBL4370940

C=CS(=O)(=O)OS(=O)(=O)C=Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.58
NFE2L2 Q16236 3/20 0.58
LMNA P02545 2/20 0.58
ALDH1A1 P00352 2/20 0.40
HTT P42858 1/20 0.40
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29204742 0.98 PPARG (0.56) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL601077 0.90 PPARG (0.68) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL17310265 0.80 PPARG (0.51) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL2402197 0.79 PPARG (0.59) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL7194001 0.78 PPARG (0.58) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL10622974 0.76 PPARG (0.50) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL131454 0.76 PPARG (0.46) PPARGNFE2L2LMNAALDH1A1
Styrene SCHEMBL16236539 0.75 PPARG (0.55) PPARGNFE2L2LMNAALDH1A1HTT
SCHEMBL2788743 0.75 PPARG (0.54) PPARGNFE2L2LMNAKMT2A
SCHEMBL10338471 0.75 PPARG (0.63) PPARGNFE2L2LMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2041236-A1 WELLBORE FLUID BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2009-04-01 EP claimed
WO-2008001049-A1 WELLBORE FLUID BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2008-01-03 WO claimed
US-6610310-B2 Immunology response; side effect reduction AMERICAN CYANAMID COMPANY 2003-08-26 US claimed
JP-60212410-A None JP disclosed
JP-S60212410-A PREPARATION OF MALEATE COPOLYMER KAO CORP 1985-10-24 JP disclosed