Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 18/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369531 | 0.87 | FSHR (0.58) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3527520 | 0.85 | FSHR (0.54) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3704579 | 0.84 | FSHR (0.67) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL4370728 | 0.84 | FSHR (0.61) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3523693 | 0.81 | FSHR (0.58) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3526977 | 0.81 | FSHR (0.58) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3397967 | 0.81 | FSHR (0.66) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3529051 | 0.79 | FSHR (0.54) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3528816 | 0.78 | FSHR (0.53) | FSHRTSHRMEN1ADRB2KMT2A | |
| SCHEMBL3527545 | 0.77 | FSHR (0.71) | FSHRTSHRMEN1ADRB2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578726-B1 | TETRAHYDROQUINOLINE DERIVATIVES | ORGANON NV (NL) | 2009-02-25 | — | — | EP | disclosed |