Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.95 |
| ▸ | F3 | P13726 | 3/20 | 0.95 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.95 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.95 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.95 |
| ▸ | GSK3B | P49841 | 1/20 | 0.70 |
| ▸ | BACE1 | P56817 | 1/20 | 0.70 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | CA3 | P07451 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631270 | 1.00 | TYR (0.95) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL4370894 | 1.00 | TYR (0.95) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL4373677 | 1.00 | TYR (0.95) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL4381938 | 1.00 | TYR (0.95) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL2146080 | 0.98 | TYR (1.00) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL3580956 | 0.98 | TYR (1.00) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL2198475 | 0.98 | TYR (1.00) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL10053044 | 0.89 | F3 (0.83) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL10943694 | 0.89 | F3 (0.83) | TYRF3HSD11B1CYP2D6CYP2C9 | |
| SCHEMBL3220874 | 0.87 | TYR (0.80) | TYRF3HSD11B1CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436197-B2 | Palladium complexes and polymerization and coupling processes thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION (US) | 2013-05-07 | — | — | US | disclosed |
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | WEST CHESTER UNIVERSITY OF PENNSYLVANIA OF THE STATE SYSTEM OF HIGHER EDUCATION | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111962-A1 | Palladium Complexes and Polymerization and Coupling Processes Thereof | DDT, PDCD2L, PDCD1LG2 | TYR 79/4885F3 1590/4885HSD11B1 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.