SCHEMBL4372385

SCHEMBL4372385

COC(=O)CCCCC(C)C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 4/20 0.44
ALDH1A1 P00352 1/20 0.44
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
RECQL P46063 1/20 0.39
LTA4H P09960 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
PPARG P37231 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580348 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL579305 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL494409 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL494385 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
Hydrochloric Acid SCHEMBL6941516 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL493846 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL494822 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL495446 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL494833 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL494661 0.98 TSHR (0.52) TSHRL3MBTL1LMNAALDH1A1PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115210310-B Compositions and methods for waste polypropylene degradation 诺弗洛普有限公司 2024-08-30 CN claimed
US-11840610-B2 Compositions and methods for the degradation of waste polypropylene NOVOLOOP, INC. (US) 2023-12-12 US claimed
CN-115210310-A Composition and method for waste polypropylene degradation 诺弗洛普有限公司 2022-10-18 CN claimed
CN-115210310-B Compositions and methods for waste polypropylene degradation 诺弗洛普有限公司 2024-08-30 CN disclosed
CN-115210310-A Composition and method for waste polypropylene degradation 诺弗洛普有限公司 2022-10-18 CN disclosed
EP-2123630-A1 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic ester derivative Taisho Pharmaceutical Co. Ltd. (JP) 2009-11-25 EP disclosed
CN-1267407-C Prodrugs of excitatory amino acids LILLY CO ELI (US) 2006-08-02 CN disclosed
CN-1486298-A Prodrugs of excitatory amino acids 2004-03-31 CN disclosed
EP-1368304-A1 PRODRUGS OF EXCITATORY AMINO ACIDS ELI LILLY AND COMPANY (US) 2003-12-10 EP disclosed
EP-1351925-A1 PRODRUGS OF EXCITATORY AMINO ACIDS ELI LILLY AND COMPANY (US) 2003-10-15 EP disclosed
WO-2002055481-A1 PRODRUGS OF EXCITATORY AMINO ACIDS ELI LILLY AND COMPANY (US) 2002-07-18 WO disclosed
WO-2002055485-A1 PRODRUGS OF EXCITATORY AMINO ACIDS ELI LILLY AND COMPANY (US) 2002-07-18 WO disclosed
WO-2002014257-A2 SYNTHESIS OF Α,Ω-DIESTERS CONSORZIO INTERUNIVERSITARIO NAZIONALE LA CHIMICA PER L'AMBIENTE (IT) 2002-02-21 WO disclosed