⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338091 | 0.94 | — | — | |
| SCHEMBL577002 | 0.94 | — | — | |
| SCHEMBL10908927 | 0.89 | — | — | |
| SCHEMBL28497078 | 0.89 | — | — | |
| SCHEMBL22713137 | 0.89 | — | — | |
| Fluoride SCHEMBL28917677 | 0.89 | — | — | |
| SCHEMBL10912154 | 0.89 | — | — | |
| Bromide SCHEMBL28527081 | 0.89 | — | — | |
| SCHEMBL29175135 | 0.80 | — | — | |
| SCHEMBL2591758 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435080-B2 | sGC stimulators | TISENTO THERAPEUTICS INC. (US) | 2025-10-07 | — | — | US | disclosed |
| CN-117865869-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aromatic amine as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114380743-B | Method for introducing trifluoromethylthio into nitrogen-containing compound | 四川大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-115894478-A | Novel pyridopyrazole heterocyclic compound and application thereof | 杭州民生药物研究院有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-112939829-B | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2023-02-21 | — | — | CN | disclosed |
| US-20220017515-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-20 | — | — | US | disclosed |
| US-11180493-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| CN-112939829-A | Synthetic method of aryl trifluoromethyl thioether | 武汉药明康德新药开发有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-109336794-B | Synthetic method of aryl vinyl trifluoro methyl sulfide compound | 江南大学 | 2020-04-07 | — | — | CN | disclosed |
| CN-109438301-B | Synthesis method of α -trifluoromethylthio substituted aromatic ketone compound | 江南大学 | 2020-03-06 | — | — | CN | disclosed |
| US-20200071318-A1 | SGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2020-03-05 | — | — | US | disclosed |
| EP-3538520-A2 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| EP-1816134-B1 | METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO (JP) | 2013-10-23 | — | — | EP | disclosed |
| US-7625639-B2 | Metal-complex compound and organic electroluminescence device using the compound | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-01 | — | — | US | disclosed |
| EP-1816134-A1 | METAL COMPLEX COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |
| US-20060115675-A1 | Metal-complex compound ands organic electroluminescence device using the compound | IDEMITSU KOSAN CO., LTD. (JP) | 2006-06-01 | — | — | US | disclosed |